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The culture of hope and ethical challenges in clinical trials: A qualitative study of oncologists and haematologists’ views
Ersta Sköndal Bräcke University College, Department of Health Care Sciences. Centre for Research Ethics & Bioethics, Uppsala University, Sweden.ORCID iD: 0000-0001-6011-6740
Rigshospitalet, Copenhagen University Hospital, Denmark.
Centrum för forsknings- och bioetik, Centre for Research Ethics & Bioethics, Uppsala universitet.ORCID iD: 0000-0001-7486-4678
Tampere University of Applied Sciences, Finland.ORCID iD: 0000-0002-0095-3683
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2019 (English)In: Clinical Ethics, ISSN 1477-7509, E-ISSN 1758-101XArticle in journal (Refereed) Published
Abstract [en]

We do not know how much clinical physicians carrying out clinical trials in oncology and haematology struggle with ethical concerns. To our knowledge, no empirical research exists on these questions in a Nordic context. Therefore, this study aims to learn what kinds of ethical challenges physicians in Sweden, Denmark and Finland (n = 29) face when caring for patients in clinical trials; and what strategies, if any, they have developed to deal with them. The main findings were that clinical cancer trials pose ethical challenges related to autonomy issues, unreasonable hope for benefits and the therapeutic misconception. Nevertheless, some physicians expressed that struggling with such challenges was not of great concern. This conveys a culture of hope where health care professionals and patients uphold hope and mutually support belief in clinical trials. This culture being implicit, physicians need opportunities to deliberately reflect over the characteristics that should constitute this culture.

Place, publisher, year, edition, pages
Sage Publications, 2019.
Keywords [en]
Clinical trials, ethics, cancer, oncology and haematology, physicians, informed consent
National Category
Ethics
Identifiers
URN: urn:nbn:se:esh:diva-7911DOI: 10.1177/1477750919897379OAI: oai:DiVA.org:esh-7911DiVA, id: diva2:1383829
Available from: 2020-01-08 Created: 2020-01-08 Last updated: 2020-01-09Bibliographically approved

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