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  • 1.
    Lindqvist, Karin
    et al.
    Stockholms universitet.
    Mechler, Jakob
    Stockholms universitet.
    Carlbring, Per
    Stockholms universitet.
    Lilliengren, Peter
    Ersta Sköndal Bräcke University College, Department of Health Care Sciences, St Lukas Educational Institute.
    Falkenström, Fredrik
    Linköpings universitet.
    Andersson, Gerhard
    Linköpings universitet; Anna Freud National Centre for Children and Families, United Kingdom.
    Johansson, Robert
    Stockholms universitet.
    Edbrooke-Childs, Julian
    Anna Freud National Centre for Children and Families, United Kingdom; University College London, United Kingdom.
    Dahl, Hanne-Sofie J.
    Sykehuset i Vestfold, Norway; Universitetet i Oslo, Norway.
    Lindert Bergsten, Katja
    Uppsala universitet.
    Midgley, Nick
    University College London, United Kingdom; Anna Freud National Centre for Children and Families, United Kingdom.
    Sandell, Rolf
    Lunds universitet.
    Thorén, Agneta
    Ericastiftelsen, Stockholm.
    Topooco, Naira
    Linköpings universitet; Center for m2 Health, USA.
    Ulberg, Randi
    Universitetet i Oslo, Norway; Dikaonhjemmet Sykehus, Norway.
    Philips, Björn
    Stockholms universitet.
    Affect-Focused Psychodynamic Internet-Based Therapy for Adolescent Depression: Randomized Controlled Trial2020In: Journal of Medical Internet Research, E-ISSN 1438-8871, Vol. 22, no 3, p. 1-15, article id e18047Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: Adolescent depression is one of the largest health issues in the world and there is a pressing need for effective and accessible treatments.

    OBJECTIVE: This trial examines whether affect-focused internet-based psychodynamic therapy (IPDT) with therapist support is more effective than an internet-based supportive control condition on reducing depression in adolescents.

    METHODS: The trial included 76 adolescents (61/76, 80% female; mean age 16.6 years), self-referred via an open access website and fulfilling criteria for major depressive disorder. Adolescents were randomized to 8 weeks of IPDT (38/76, 50%) or supportive control (38/76, 50%). The primary outcome was self-reported depressive symptoms, measured with the Quick Inventory of Depressive Symptomatology for Adolescents (QIDS-A17-SR). Secondary outcomes were anxiety severity, emotion regulation, self-compassion, and an additional depression measure. Assessments were made at baseline, postassessment, and at 6 months follow-up, in addition to weekly assessments of the primary outcome measure as well as emotion regulation during treatment.

    RESULTS: IPDT was significantly more effective than the control condition in reducing depression (d=0.82, P=.01), the result of which was corroborated by the second depression measure (d=0.80, P<.001). IPDT was also significantly more effective in reducing anxiety (d=0.78, P<.001) and increasing emotion regulation (d=0.97, P<.001) and self-compassion (d=0.65, P=.003). Significantly more patients in the IPDT group compared to the control group met criteria for response (56% vs 21%, respectively) and remission (35% vs 8%, respectively). Results on depression and anxiety symptoms were stable at 6 months follow-up. On average, participants completed 5.8 (SD 2.4) of the 8 modules.

    CONCLUSIONS: IPDT may be an effective intervention to reduce adolescent depression. Further research is needed, including comparisons with other treatments.

    TRIAL REGISTRATION: International Standard Randomised Controlled Trial Number (ISRCTN) 16206254; http://www.isrctn.com/ISRCTN16206254.

  • 2.
    Sveen, Josefin
    et al.
    Uppsala universitet.
    Andersson, Gerhard
    Linköpings universitet.
    Buhrman, Bo
    Linköpings universitet.
    Sjöberg, Folke
    Linköpings universitet.
    Willebrand, Mimmie
    Uppsala Universitet.
    Internet-based information and support program for parents of children with burns: A randomized controlled trial.2017In: Burns, ISSN 0305-4179, E-ISSN 1879-1409, Vol. 43, no 3, p. 583-591Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: The aim of the study was to evaluate the feasibility and effects of an internet-based information and self-help program with therapist contact for parents of children and adolescents with burns. The program aimed to reduce parents' symptoms of general and posttraumatic stress.

    METHODS: Participants were parents of children treated for burns between 2009-2013 at either of the two specialized Swedish Burn centers. Sixty-two parents were included in a two-armed, randomized controlled trial with a six-week intervention group and a wait-list control group, including a pre and post-assessment, as well as a 3 and 12-month follow-up. The intervention contained psychoeducation, exercises and homework assignments, and the intervention group received weekly written feedback from a therapist. The main outcome was stress (post-traumatic stress, general stress and parental stress).

    RESULTS: The program had a beneficial effect on posttraumatic stress in the short term, but did not affect general stress or parental stress. The parents rated the program as being informative and meaningful, but some of them thought it was time-consuming.

    CONCLUSION: The program has the potential to support parents of children with burns. The intervention is easily accessible, cost-effective and could be implemented in burn care rehabilitation.

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